Positive context积极背景
Stocks股票 / Health Care / TWST
Twist Bioscience Corp · Health Care
TWST US listed · USD美股 · 美元
Health Care
Russell 2000罗素2000
Speculative / unprofitable投机／未盈利
$132.75
Regular quote常规时段报价
-$11.74 · -8.13%
Extended quote unavailable. Showing the regular quote.盘前盘后报价暂不可用，现显示常规时段报价。
Pre-market盘前
·
52w low52周低 $24.36high高 $211
Extended — wait for a pullback过度拉伸 — 等待回撤
A cycle low is due in roughly ~0–15 trading days — watch for the turn, don't front-run it.周期低点预计在约 ~0–15 个交易日内出现——等待转向，切勿抢跑。
As of 2026-10-26截至 2026-10-26
Company news公司新闻
The latest reporting最新报道
One story, with the reporting behind it.将同一事件汇总，保留各来源报道。
Company intelligence公司情报
The latest call, in context把最新财报放回历史脉络
A synthesized event record across management commentary and recorded metrics. Read as context; verify exact wording in the transcript before relying.综合管理层表述与记录指标形成事件档案。仅供参考；使用前请在电话会原文中核对准确措辞。
Live company record实时公司记录
JavaScript loads the source-bounded event record here. Open Terminal if the live module does not start.JavaScript 会在此加载受来源约束的事件记录。如实时模块未启动，请打开终端。
Continue with full transcript history继续查看完整电话会历史 ↗Pressure context压力背景
History mode历史模式
Context only仅供参考 · not a signal or recommendation不构成信号或建议
Narrative claims may await line-level citation; verify in the transcript.叙述性内容可能仍待逐行引用，请在电话会原文中核对。
Price chart价格图表
daily · interactive日线 · 可交互
Open in Terminal打开终端 ↗
Loading chart…图表加载中…
The interactive chart could not load here.互动图表暂时无法在此加载。
Open the live chart in Terminal在终端中打开实时图表 ↗
Candles, volume and moving averages — pan and zoom inside the chart.蜡烛图、成交量与均线 — 图内可缩放拖动。
MMastermind Terminal — live & interactiveMastermind 终端 — 实时互动 ↗
Technicals技术面
daily bars日线数据 · 2026-10-26
Momentum (RSI 14)动量（RSI 14）
38
Depressed偏低
vs 50-day average相对50日均线
-10.2% below下方
Below trend跌破趋势
vs 200-day average相对200日均线
+59.4% above上方
Long trend up长期向上
Volatility波动率
93th percentile第93百分位
These readings feed the stance at the top — one source per number, refreshed nightly.以上读数构成页首的引擎立场 — 每个数字只有一个来源，每晚更新。
Earnings财务业绩
next report下次财报 2026-11-1319
Mixed — beat 0 of last 4 quarters表现不稳 — 近 4 季中 0 季超预期
Post-earnings drift: +40.3% (20d)财报后漂移：+40.3%（20日）
EPS surprise vs consensus, last quarters每股收益相对预期的超预期幅度（近几个季度） · average平均 -10.9%
Financials财务数据
fiscal years财年Revenue营业收入
$376.6M2025
20202025
5-yr growth5年复合增速 33.1%
Earnings per share每股收益
$-1.302025
20202025
Free cash flow自由现金流
-$75.6M2025
20202025
Operating margin营业利润率
-36.2%
Balance-sheet quality财务体质 4/8
Return on equity股本回报率 -17%
Clean稳健
Leverage杠杆
Current ratio流动比率3.64
Capital allocation资本配置
Stock-based comp股权薪酬$64.5M
Share count change (1y)股数变化（1年）+2.8%
Debt coming due到期债务
FY2021 10-KIn the 12-month bucket following fiscal period end 2021-09-30, it reported $833.0K due — about 100% of its disclosed principal.在财年期末 2021-09-30 之后12个月的区间内，已披露到期本金为 $833.0K，约占其披露本金的 100%。
All maturity buckets are measured from fiscal period end 2021-09-30, not from today.所有到期区间均从财年期末 2021-09-30 起算，而非从今天起算。
First 12 months after period end报告期末之后首12个月
$833.0K
Year 2第2年
not reported未披露
Year 3第3年
not reported未披露
Year 4第4年
not reported未披露
Year 5第5年
not reported未披露
After year 55年以后
not reported未披露
Cash reported at 2025-09-30: $183049000.截至 2025-09-30 披露的现金：$183049000。 At the cash-burn pace reported over 2024-10-01 to 2025-09-30, that cash represented about 29.0 months. This scenario excludes debt payments and future financing.按 2024-10-01 至 2025-09-30 期间披露的现金消耗速度，该现金约对应 29.0 个月。此情景不包括债务偿还与未来融资。
Capital-need coverage is partial; incomplete or incompatible filing inputs are not combined.资本需求覆盖信息不完整；不会合并不完整或不兼容的报告数据。
Any available cash-flow scenario is context only. Missing or incompatible inputs are not replaced with zero or a financing forecast.可用现金流情景仅供参考；缺失或不兼容的输入不以零值或融资预测替代。
Sources and cash-flow calculation来源与现金流计算
Figures are XBRL facts from one filing — no two years are mixed. Filing数据取自同一份文件中的 XBRL 事实，不跨文件拼接。文件
0001104659-21-142700, period ending报告期截至 2021-09-30, unit单位 USD.
Cache acquired缓存获取时间: 2026-10-04T09:26:23.666778+00:00.
1/6 buckets reported.个区间有披露。
LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonthsLongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo— period_mismatchLongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree— period_mismatchLongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour— absentLongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive— absentLongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive— absent
Annual period年度区间 2024-10-01 — 2025-09-30 · USD · 10-K · 0001581280-25-000025 · Filed提交日期 2025-11-17.
Cache acquired缓存获取时间: 2026-10-04T09:26:23.666778+00:00 · Evaluated as of评估截至 2026-10-26.
- Reported operating cash flow已披露经营活动现金流: $-47628000
- Reported equipment spending (capex outflow)已披露设备支出（资本开支流出）: $28004000
- Derived free cash flow (operating cash flow minus capex)计算所得自由现金流（经营现金流减资本开支）: $-75632000
Cash is the reported balance at period end. The runway scenario holds this annual cash-flow pace constant and excludes debt payments, restricted-cash adjustments and future financing.现金为期末已披露余额。现金跑道情景假设本年度现金流速度保持不变，不包括债务偿还、受限现金调整与未来融资。
Research context only — reported figures from SEC filings, not a rating, a signal or investment advice.仅供研究参考 — 数据摘自 SEC 文件披露口径，不构成评级、信号或投资建议。
Why is it moving为何波动
6 checks · nightly六项检查 · 每晚
Positioning持仓
Insider cluster activity内部人集中交易
Technical技术面
BOTTOMING → UNCONFIRMED TURN筑底中 → 未确认转向
Ownership & smart money持仓与聪明钱
13FInsider activity:内部人动向： -$115.2M net (0 buyers, 10 sellers)-$115.2M 净值（0 买家，10 卖家）
Concentrated ownership集中持仓
| Fund基金 | Grade评级 | Latest move最新动作 | % of book组合占比 | As of截至 |
|---|---|---|---|---|
| Polen Capital Management | C | Adding加仓 | 0.1% | 2026-06-30 |
| Perceptive Advisors | A | trimtrim | 0.1% | 2026-06-30 |
| Duquesne Family Office (Druckenmiller) | C | exitexit | 0.0% | 2026-06-30 |
Signal history信号历史
engine events引擎事件
UNCONFIRMED TURN → NEARING A LOW未确认转向 → 接近低点
GET READY. Day 29 of a typical 23-44-day cycle — inside the window where lows usually form, and short-term momentum is washed out. No confirmed turn yet准备。典型 23-44 天周期的第 29 天——处于低点通常形成的窗口内，且短期动量已被洗净。尚无确认的转向
Oct 13, 2026
BOTTOMING → UNCONFIRMED TURN筑底中 → 未确认转向
HIGH-RISK · NIMBLE ONLY高风险 · 仅限灵活操作
Oct 7, 2026
TWST daily MACD crossed downTWST 日线MACD下穿
The daily MACD histogram turned negative — fast and noisy, context rather than a standalone trigger. $155.65.日线MACD柱状图转负 — 快速且嘈杂，仅作背景。$155.65。
Oct 6, 2026
NEARING A HIGH → BOTTOMING接近高点 → 筑底中
BUY SETUP买入预备
Oct 5, 2026
TWST made a new 52-week highTWST 创52周新高
Price reached a fresh 52-week high — a momentum / trend extreme the whole market watches. $205.00.价格创出52周新高 — 全市场关注的动量/趋势极值。$205.00。
Sep 29, 2026
TWST made a new 52-week highTWST 创52周新高
Price reached a fresh 52-week high — a momentum / trend extreme the whole market watches. $186.13.价格创出52周新高 — 全市场关注的动量/趋势极值。$186.13。
Sep 24, 2026
TWST made a new 52-week highTWST 创52周新高
Price reached a fresh 52-week high — a momentum / trend extreme the whole market watches. $184.03.价格创出52周新高 — 全市场关注的动量/趋势极值。$184.03。
Sep 24, 2026
TWST RSI reached overboughtTWST RSI进入超买
RSI(14) crossed above 70 — stretched to the upside; context, not a timing trigger alone. $184.03.RSI(14)上穿70 — 上行过度；仅作背景，单独不构成择时。$184.03。
Sep 18, 2026
TWST RSI reached overboughtTWST RSI进入超买
RSI(14) crossed above 70 — stretched to the upside; context, not a timing trigger alone. $166.99.RSI(14)上穿70 — 上行过度；仅作背景，单独不构成择时。$166.99。
Showing the last 15 of显示最近15条，共 162 signals条信号
Company profile公司档案
Watch items — what could change the story关注项 — 可能改变故事的因素
- Receivables stretch
- Capital intensity rising
The whole US universe — S&P 1500 and Russell 2000 — read nightly.覆盖标普1500与罗素2000全部成分股 — 每晚更新解读。
Signals, options positioning, smart-money moves and factor DNA — the same engine that wrote this page covers 2,700+ US stocks.信号、期权持仓、聪明钱动向与因子基因 — 撰写本页的引擎覆盖2700多只美股。
Statistics — full detail统计数据 — 完整明细
Price history价格历史
| Period周期 | This stock本股 | S&P 500标普500 |
|---|---|---|
| 1 Week近1周 | -16.9% | -2.0% |
| 1 Month近1月 | -7.2% | +1.5% |
| 3 Months近3月 | +41.4% | +2.9% |
| 6 Months近6月 | +122.0% | +8.0% |
| Year to date年初至今 | +309.8% | +12.6% |
| 1 Year近1年 | +331.7% | +16.8% |
Trading information交易信息
Volatility rank波动率分位
93th pctile
EPS (trailing)每股收益
$-1.27
Off 52-week high距52周高点
-35.2%
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Financials — full detail财务数据 — 完整明细
Multi-year record多年财务记录
| 20202020 | 20212021 | 20222022 | 20232023 | 20242024 | 20252025 | |
|---|---|---|---|---|---|---|
| Revenue营业收入 | $90M | $132M | $204M | $245M | $313M | $377M |
| EPS每股收益 | $-3.57 | $-3.15 | $-4.04 | $-3.60 | $-3.60 | $-1.30 |
| Free cash flow自由现金流 | $-152M | $-139M | $-226M | $-170M | $-69M | $-76M |
| Gross margin毛利率 | 31.8% | 39.1% | 41.4% | 36.6% | 42.6% | 50.7% |
| Net margin净利率 | -155.3% | -114.9% | -107.0% | -83.5% | -66.7% | -20.6% |
| FCF margin自由现金流利润率 | -168.8% | -105.3% | -111.1% | -69.5% | -22.1% | -20.1% |
Latest fiscal year最近财年
Net income净利润
$-78M
Operating cash flow经营现金流
$-48M
Total assets总资产
$638M
Shareholder equity股东权益
$456M
Shares outstanding总股本
0.06B
Returns & growth回报与增长
Return on equity股本回报率
-17.0%
Return on assets资产回报率
-12.2%
Asset growth资产增速
+4.8%
Accounting quality checks会计质量检查
- Earnings quality: earnings cash-backed盈利质量：盈利有现金支撑
- Working capital: inventory & receivables lean vs sales营运资本：存货与应收相对销售保持精简
- Pricing power: gross margin +18.9pts over 6 years定价能力：毛利率 6 年上升 18.9 个百分点
- Capital discipline: share count +34.5% over 6 years (dilution)资本纪律：股本 6 年增加 34.5%（稀释）
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Technicals — full detail技术面 — 完整明细
Indicator readings指标读数
RSI (14-day)RSI（14日）
38
RSI (2-day)RSI（2日）
2
vs 20-day average相对20日均线
-21.0%
vs 50-day average相对50日均线
-10.2%
vs 200-day average相对200日均线
+59.4%
Golden cross (50>200)金叉（50>200）
in effect生效中
MACDMACD
below signal位于信号线下方
Timeframe alignment多周期共振
Daily日线
momentum down动能向下
3-day3日线
momentum down — fresh downturn动能向下——刚刚转弱
Weekly周线
momentum up动能向上
When daily through monthly point the same way, moves carry further.当日线到月线方向一致时，行情往往更有延续性。
Volatility regime波动状态
Range state波幅状态
expanding — range opening up扩张中 — 波幅放大
Range width percentile波幅宽度分位
80/100
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Earnings — full detail财务业绩 — 完整明细
Surprise history超预期历史
| Quarter季度 | Reported实际 | Expected预期 | Surprise超预期 |
|---|---|---|---|
| Jun 2026 | $-0.56 | $-0.50 | -12.0% |
| Mar 2026 | $-0.62 | $-0.54 | -14.8% |
| Dec 2025 | $-0.50 | $-0.48 | -4.2% |
| Sep 2025 | $-0.45 | $-0.40 | -12.5% |
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Ownership — full detail持仓 — 完整明细
Tracked funds holding it跟踪基金持仓
| Fund基金 | Grade评级 | Latest move最新动作 | % of book组合占比 | Position市值 |
|---|---|---|---|---|
| Polen Capital Management | C | Adding增持 | 0.1% | $6M |
| Perceptive Advisors | A | Trimming减持 | 0.1% | $4M |
| Duquesne Family Office (Druckenmiller) | C | Exited清仓 | 0.0% | $10M |
Fund positioning基金持仓概览
Tracked funds in the name持有该股的跟踪基金
3
Buying vs selling买入vs卖出
1 : 2
Insiders & shorts内部人与空头
Insider net buying (6 months)内部人净买入（6个月）
-$115.2M
Insider buyers vs sellers内部人买家vs卖家
0 : 10
Recent fund flows近期基金流向
ARKKARKK
trimming减持
ROBO Global Healthcare Technology & InnovationROBO Global Healthcare Technology & Innovation
trimming减持
ARK Genomic RevolutionARK Genomic Revolution
trimming减持
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。