Positive context积极背景
Stocks股票 / SYRE
Spyre Therapeutics Inc
SYRE US listed · USD美股 · 美元
Russell 2000罗素2000
Speculative / unprofitable投机／未盈利
$104.09
+$1.35 · +1.31%
52w low52周低 $14.45high高 $108
Extended — wait for a pullback过度拉伸 — 等待回撤
Stretched/late — protect gains and don't start new positions; let the next low set up first.已拉伸／晚期——保护利润，不要新开仓；先等下一个低点构筑成形。
Live实时
Company intelligence公司情报
The latest call, in context把最新财报放回历史脉络
A synthesized event record across management commentary and recorded metrics. Read as context; verify exact wording in the transcript before relying.综合管理层表述与记录指标形成事件档案。仅供参考；使用前请在电话会原文中核对准确措辞。
Live company record实时公司记录
JavaScript loads the source-bounded event record here. Open Terminal if the live module does not start.JavaScript 会在此加载受来源约束的事件记录。如实时模块未启动，请打开终端。
Continue with full transcript history继续查看完整电话会历史 ↗Pressure context压力背景
History mode历史模式
Context only仅供参考 · not a signal or recommendation不构成信号或建议
Narrative claims may await line-level citation; verify in the transcript.叙述性内容可能仍待逐行引用，请在电话会原文中核对。
Price chart价格图表
daily · interactive日线 · 可交互
Open in Terminal打开终端 ↗
Loading chart…图表加载中…
The interactive chart could not load here.互动图表暂时无法在此加载。
Open the live chart in Terminal在终端中打开实时图表 ↗
Candles, volume and moving averages — pan and zoom inside the chart.蜡烛图、成交量与均线 — 图内可缩放拖动。
MMastermind Terminal — live & interactiveMastermind 终端 — 实时互动 ↗
Technicals技术面
daily bars日线数据 · 2026-08-14
Momentum (RSI 14)动量（RSI 14）
57
Neutral zone中性区域
vs 50-day average相对50日均线
+12.5% above上方
Uptrend intact趋势完好
vs 200-day average相对200日均线
+87.2% above上方
Long trend up长期向上
Volatility波动率
57th percentile第57百分位
These readings feed the stance at the top — one source per number, refreshed nightly.以上读数构成页首的引擎立场 — 每个数字只有一个来源，每晚更新。
Earnings财务业绩
Financials财务数据
fiscal years财年
Return on equity股本回报率 -22%
Clean稳健
Capital allocation资本配置
Share count change (1y)股数变化（1年）+29.8%
Why is it moving为何波动
6 checks · nightly六项检查 · 每晚
Positioning持仓
Insider cluster activity内部人集中交易
Technical技术面
SYRE took relative-strength leadershipSYRE 取得相对强弱领先
Ownership & smart money持仓与聪明钱
13FInsider activity:内部人动向： -$3.2M net (0 buyers, 2 sellers)-$3.2M 净值（0 买家，2 卖家）
Concentrated ownership集中持仓
| Fund基金 | Grade评级 | Latest move最新动作 | % of book组合占比 | As of截至 |
|---|---|---|---|---|
| Perceptive Advisors | A | Adding加仓 | 3.8% | 2026-03-31 |
| RTW Investments | B | Holding持有 | 2.1% | 2026-03-31 |
| RA Capital Management | D | Holding持有 | 0.9% | 2026-03-31 |
| Baker Bros. Advisors | A | Holding持有 | 0.3% | 2026-03-31 |
Signal history信号历史
engine events引擎事件
UNCONFIRMED TURN → NEARING A HIGH未确认转向 → 接近高点
TAKE PROFITS. Late in the daily cycle (day 58 of ~23-44) — odds favor a dip into the next cycle low from here even with the trend intact止盈。处于日线周期晚期（约 23-44 天中的第 58 天）——即便趋势完好，从此处概率上仍倾向于回落至下一个周期低点
Aug 7, 2026
SYRE took relative-strength leadershipSYRE 取得相对强弱领先
Relative strength vs SPY crossed above the 90th percentile of the last 90 days — leadership tends to persist. $104.91.相对标普500的强弱上穿近90日的第90百分位 — 领先往往延续。$104.91。
Aug 7, 2026
SYRE made a new 52-week highSYRE 创52周新高
Price reached a fresh 52-week high — a momentum / trend extreme the whole market watches. $104.91.价格创出52周新高 — 全市场关注的动量/趋势极值。$104.91。
Aug 4, 2026
UNCONFIRMED TURN → NEARING A HIGH未确认转向 → 接近高点
TAKE PROFITS止盈
Aug 4, 2026
SYRE took relative-strength leadershipSYRE 取得相对强弱领先
Relative strength vs SPY crossed above the 90th percentile of the last 90 days — leadership tends to persist. $104.94.相对标普500的强弱上穿近90日的第90百分位 — 领先往往延续。$104.94。
Aug 4, 2026
SYRE made a new 52-week highSYRE 创52周新高
Price reached a fresh 52-week high — a momentum / trend extreme the whole market watches. $104.94.价格创出52周新高 — 全市场关注的动量/趋势极值。$104.94。
Aug 4, 2026
SYRE StochRSI turned up from oversoldSYRE StochRSI自超卖区上行
StochRSI popped back above 20 — the earliest oscillator heads-up that downside momentum is easing. $104.94.StochRSI重回20上方 — 下行动量趋缓的最早预警。$104.94。
Jul 31, 2026
NEARING A HIGH → BOTTOMING接近高点 → 筑底中
BUY SETUP买入预备
Jul 30, 2026
BOTTOMING → NEARING A HIGH筑底中 → 接近高点
TAKE PROFITS止盈
Jul 29, 2026
NEARING A HIGH → BOTTOMING接近高点 → 筑底中
BUY SETUP买入预备
Jul 22, 2026
SYRE daily MACD crossed downSYRE 日线MACD下穿
The daily MACD histogram turned negative — fast and noisy, context rather than a standalone trigger. $99.17.日线MACD柱状图转负 — 快速且嘈杂，仅作背景。$99.17。
Jul 21, 2026
SYRE made a new 52-week highSYRE 创52周新高
Price reached a fresh 52-week high — a momentum / trend extreme the whole market watches. $102.70.价格创出52周新高 — 全市场关注的动量/趋势极值。$102.70。
Jul 21, 2026
SYRE daily MACD crossed upSYRE 日线MACD上穿
The daily MACD histogram turned positive — fast and noisy, context rather than a standalone trigger. $102.70.日线MACD柱状图转正 — 快速且嘈杂，仅作背景。$102.70。
Showing the last 15 of显示最近15条，共 145 signals条信号
Company profile公司档案
The whole US universe — S&P 1500 and Russell 2000 — read nightly.覆盖标普1500与罗素2000全部成分股 — 每晚更新解读。
Signals, options positioning, smart-money moves and factor DNA — the same engine that wrote this page covers 2,700+ US stocks.信号、期权持仓、聪明钱动向与因子基因 — 撰写本页的引擎覆盖2700多只美股。
Statistics — full detail统计数据 — 完整明细
Price history价格历史
| Period周期 | This stock本股 | S&P 500标普500 |
|---|---|---|
| 1 Week近1周 | -0.2% | +0.4% |
| 1 Month近1月 | +11.1% | +3.1% |
| 3 Months近3月 | +37.6% | +3.3% |
| 6 Months近6月 | +184.2% | +13.6% |
| Year to date年初至今 | +240.4% | +13.4% |
| 1 Year近1年 | +555.1% | +21.2% |
Trading information交易信息
Volatility rank波动率分位
57th pctile
EPS (trailing)每股收益
$-1.98
Off 52-week high距52周高点
-1.2%
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Financials — full detail财务数据 — 完整明细
Latest fiscal year最近财年
Revenue (FY)营业收入（财年）
$0
Net income净利润
$-155M
Operating cash flow经营现金流
$-169M
Total assets总资产
$778M
Shareholder equity股东权益
$715M
Shares outstanding总股本
0.08B
Returns & growth回报与增长
Return on equity股本回报率
-21.7%
Return on assets资产回报率
-20.0%
Asset growth资产增速
+27.8%
Accounting quality checks会计质量检查
- Earnings quality: accruals near the peer median盈利质量：应计利润接近同业中位
- Capital discipline: investment near the peer median资本纪律：投资力度接近同业中位
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Technicals — full detail技术面 — 完整明细
Indicator readings指标读数
RSI (14-day)RSI（14日）
57
RSI (2-day)RSI（2日）
56
vs 20-day average相对20日均线
+3.2%
vs 50-day average相对50日均线
+12.5%
vs 200-day average相对200日均线
+87.2%
Golden cross (50>200)金叉（50>200）
in effect生效中
MACDMACD
below signal位于信号线下方
Timeframe alignment多周期共振
Daily日线
momentum down动能向下
3-day3日线
momentum down — fresh downturn动能向下——刚刚转弱
Weekly周线
momentum up动能向上
When daily through monthly point the same way, moves carry further.当日线到月线方向一致时，行情往往更有延续性。
Volatility regime波动状态
Range width percentile波幅宽度分位
8/100
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。
Ownership — full detail持仓 — 完整明细
Tracked funds holding it跟踪基金持仓
| Fund基金 | Grade评级 | Latest move最新动作 | % of book组合占比 | Position市值 |
|---|---|---|---|---|
| Perceptive Advisors | A | Adding增持 | 3.8% | $191M |
| RTW Investments | B | Holding持有 | 2.1% | $210M |
| RA Capital Management | D | Holding持有 | 0.9% | $82M |
| Baker Bros. Advisors | A | Holding持有 | 0.3% | $50M |
Fund positioning基金持仓概览
Tracked funds in the name持有该股的跟踪基金
4
Buying vs selling买入vs卖出
1 : 0
Quarterly trend季度趋势
{'direction': 'accumulating', 'n_quarters': 11, 'holders_first': 1, 'holders_last': 4, 'holders_delta': 3, 'value_change_pct': 53589.4, 'from_period': '2023-09-30', 'to_period': '2026-03-31', 'available_on': '2026-05-16', 'available_on_first': '2023-11-15', 'holders_series': [1, 2, 3, 3, 3, 3, 3, 3, 3, 4, 4]}{'direction': 'accumulating', 'n_quarters': 11, 'holders_first': 1, 'holders_last': 4, 'holders_delta': 3, 'value_change_pct': 53589.4, 'from_period': '2023-09-30', 'to_period': '2026-03-31', 'available_on': '2026-05-16', 'available_on_first': '2023-11-15', 'holders_series': [1, 2, 3, 3, 3, 3, 3, 3, 3, 4, 4]}
Insiders & shorts内部人与空头
Insider net buying (6 months)内部人净买入（6个月）
-$3.2M
Insider buyers vs sellers内部人买家vs卖家
0 : 2
Recent fund flows近期基金流向
SPDR S&P BiotechSPDR S&P Biotech
trimming减持
Research context only — refreshed nightly. Not investment advice.仅供研究参考 — 每晚更新，不构成投资建议。